PROTEIN CRYSTALLOGRAPHY BEYOND 2000

HIGH THROUGHPUT AND HIGH QUALITY

1-2 September, 2001

Krynica, Poland

A Satellite Conference of the 20th European Crystallographic Meeting Kraków, Poland

This conference will be held parallel with the International Symposium on Synchrotron Crystallography (SYNCRYS), some lectures will be addressed to participants of both conferences.

ORGANIZERS

• Szymon Krzywda, University of York, UK - Chairman
• Krzysztof Lewinski, Jagiellonian University, Poland - Co-Chairman
• Mariusz Jaskolski, Adam Mickiewicz University, Poland
• Marek Brzozowski, University of York, UK
• in cooperation with the Macromolecular Crystallography SIG

PROGRAM COMMITTEE

• Keith Wilson (UK) - Chairman
• Jan Drenth (Netherlands)
• Viktor Lamzin (Germany)
• Alberto Podjarny (France)
• Maria A. Carrondo (Portugal)
• Dusan Turk (Slovenia)
• Susan Bailey (UK)

SCIENTIFIC PROGRAM

Section I:Expression, Crystallisation & High Throughput

         Lecture 1: Optimization of protein expression in bacteria
                    and eucaryotes - Anthony J. Wilkinson,
                    University of York

         Lecture 2: Crystallogenesis: theory and methods. Marek A.
                    Brzozowski, University of York

         Lecture 3: The Berlin Protein Structure Factory - High
                    throughput crystallographic and NMR analysis
                    of pharmaceutically and medically important
                    proteins. Patrick Umbach, Protein Structure
                    Factory, Berlin

Section II: Bioinformatics & Structural Genomics

         Lecture 1: Predicting functions and protein-protein
                    interactions from 3D structures in the context
                    of Structural Genomics. Rob Russell,
                    EMBL Heildelberg

         Lecture 2: Information Flow in Structural Genomics Projects.
                     R. Pielaszek & Wladek Minor, University of Virginia

         Lecture 3: Trapping and visualization of the catalytic
                    intermediates in Alkaline Phosphatase, Bogdan Stec,
                    Rice University

Section III: X-ray/Sources/Data acquisition

         Lecture 1: Data acquisition - Sean McSweeney, ESRF Grenoble

         Lecture 2: Choice of Data Collection parameters in X-ray
                    protein crystallography. Alexander Popov,
                    EMBL Hamburg

Section IV: Phasing/Refinement

         Lecture 1: S/I/Br Phasing. Zbyszek Dauter, BNL Brookhaven

         Lecture 2: Automated Molecular Replacement.
                    Chuck Kissinger Structural GenomiX

         Lecture 3: Averaging etc. Eleanor Dodson, University of York

         Lecture 4: Averaging - practical examples.
                    Dusan Turk, University of Ljublana

         Lecture 5: Maximum Likelihood (Refmac).
                    Garib Marshudow, CCP4 Deresbury

         Lecture 6: High Resolution Structures. Keith Wilson,
                    University of York

         Closing Lecture: Guy Dodson, MRC Mill Hill

         Tutorial 1: HKL2000. Wladek Minor, University of Virginia
         Tutorial 2: CCP4i. Martyn Winn, CCP4 Daresbury

CONFERENCE SITE AND TIME

The conference will be held in Krynica, popular resort in Beskidy Mountains about 150 km from Krakow. Participants will be located in Czarny Potok Conference Center, all lectures will be on site.

Free-of-charge bus from Krakow to Krynica will be provided for participants on August 31, in the afternoon. Return bus to Krakow Airport and train station will be provided in the morning on September 3 and September 4 (for participants staying for SYNCRYS).

CONFERENCE FEE

The fee for all participants is 280 EUR. It covers registration, conference materials, accommodation, full board and social events. No additional fee is required for participation in third day of SYNCRYS conference.

The payment should be made by bank transfer to:

Jagiellonian University BOIN, Bank BPH IV O/Krakow

Account number 10601389-330000157610 (please indicate PCB2K)

 

REGISTRATION

Registration should be send to Szymon Krzywda by email: szymon@yorvic.york.ac.uk

Include: Title, First Name, Family Name, Affiliation and mailing address, E-mail, short CV and indicate if you are applying for financial support.

 

DEADLINES

Deadline for application for financial support is May 31, 2001.

Deadline for registration is May 31, 2001.

The conference is sponsored by GlaxoSmithKline

last update August 1, 2001 (K.Lewinski)